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Herbal Formulations
S.No Title Inventors and Team Country/Patent No./Grant Date Summary
         
 
1 Synergistic anti -malarial formulation
GP Dutta,
DC Jain,
RS Bhakuni,
S. Saxena,
Sangeeta Dhawan,
SPS Khanuja,
Sushil Kumar, 
Renu Bajpai,
Aseem Umesh,
Nuzhhat Kamal,
AK Dwivedi,
Satyavan Singh
South Africa/ 2002/8485/31.12.2003
India/211247/23.10.2007
 
 
The invention relates to a synergistic formulation comprising pharmaceutically effective amount of alpha/beta. arteether and a neutralized refined vegetable oil suitable for administration by rectal route. The invention also provides the method for the treatment of cerebral and comatose malaria and process for the preparation of the said formulation. 
 
2 Mosquito repellent composition and process for preparation of the same
Dinesh Kumar, 
YN Shukla,
Shikha Tiwari,
RP Bansal,
Sushil Kumar
 
Srilanka/12380/23.9.2005
 
 
Mosquito repellant formulation has been developed from essential oils of Tagetus minuta, cedarwood and powder of Pyrethrum flowers. The formulation can be prepared in the form of agarbattis which upon burning show strong repellency against mosquitoes.
 
3 Anti-fungal formulation active against a broad spectrum of dermatophytoses
SK Shahi,
AC Shukla,
Anupam Dikshit,
Ashok Kumar Bajaj,
AK Singh, 
Sushil Kumar
 
USA/6312698/6.11.2001
India/226628/22.12.2008
 
The invention provides a novel anti-fungal formulation active against a broad spectrum of dermatophytoses, comprising oil extracted from Rabdosia melissoides and one or more vegetable oils, solvents and additives. Most of the topical creams available in the market are fungistatic and there is recurrence of the infection after discontinuance of the medicines. However, the present formulation was highly effective with fungicidal action where infection is completely eliminated and there is no recurrence of the infection.
 
4 Formulation of dihydro-artemisinin for the control of wide spectrum of malaria
DC Jain,
RS Bhakuni,
RP Sharma,
Sushil Kumar,
GP Dutta
 
Australia/763680/13.11.2003
China/CN 1197568 C/20.4.2005
Germany/France/Great Britain1034794/30.5.2007
Japan/3686281/10.6.2005
Srilanka/11674/6.6.2000
Malaysia/129619/30.4.2007
Netherland/1034794/30.5.2007
Pakistan/136849/26.7.2001
USB/6362219/26.3.2002
USA/6214864/10.4.2001
South Africa/99/2354/29.11.2000
India/191696/26.8.2004
 
The invention relates to a synergistic formulation comprising of pharmaceutically effective amount of DHA and a vegetable oil useful for the control of wide spectrum of malarial infections.
 
5 Pharmaceutical composition containing cow urine distillate as an antibiotic
SPS Khanuja,
Sushil Kumar,
AK Shasany,
JS Arya,
MP Darokar,
Monika Singh,
Prachi Sinha,
Soumya Awasthi,
SC Gupta,
VK Gupta,
MM Gupta,
RK Verma,
Sweta Agarwal,
SB Mansinghka,
SH Dawle
 
South Africa/2003/2276/28.4.2004
 
A novel bioactive fraction has been isolated from cow urine distillate which acts as highly effective bioenhancer of anti-infective, anticancer agents and nutrients (US Patent No. 6,410,059). Using this important lead novel pharmaceutical composition can be prepared in which the said fraction from cow urine distillate acts as bioavailability facilitator to the bioactive compounds like anticancer agents antibiotics, drugs, therapeutic and nutraceutical agents, ions and similar molecules. The bioenhancement activity of different fractions of the cow urine distillate in combination with antibiotics and anticancer compound taxol has been proven at GRB Division of CIMAP through in vitro testing on different pathogenic bacterial strains and cancer cell lines respectively
 
6 An improved formulation for the preparation of multipurpose insect repellent Dhoop batti  Dinesh Kumar, 
YN Shukla,
Shikha Tiwari,
RP Bansal,
Sushil Kumar
 
India/194307/3.2.2006
 
The herbal insect repellent composition of the present invention contains natural essential oils of citronella, cedarwood, pyrethrum flower powder and Artemisia annua oil which have been found to have synergistic action for insect repellency. Natural essential oils used in the composition have repellency against houseflies and mosquitoes and also have pleasant odour. Many oxygenated terpenes like carvacrol, citral, citronellol, eugenol, farnesol and geraniol isolated from various essential oils have been found effective against Aedes aegypti. Some of these essential oils also bring about inhibition in the orientation and development of housefly eggs in which acute toxicity and inhibition in metamorphosis have been observed. Cedarwood oil is also considered as having very good insecticidal activity against housefly Musca domestica L.
 
7 An analgesic and refreshing herbal composition useful as dentrifrices
AK Singh,
RL Bindra,
YN Shukla,
Rashmi Gupta,
Sushil Kumar 
India/239740/31.3.2010
 
The invention provides an analgesic and refreshing herbal composition useful as dentrifrices, said composition comprising 50-60% Wt. of betle extract (from Piper betle leaves); 40-50% Wt. of one or more group I essential oil selected from Levender officinal, Dementholised oil (ex-Mentha arvensis), Fennel oil and Ocimum gratissimum; 3.5-6% Wt. of one or more group II essential oils and their isolates selected from Ocimum Sanctum, Pulegone (ex Mentha pulegonium), Carvone (ex. Dill seed) and Menthol (ex. Mentha arvensis); 1-5% Wt. of one or more group III essential oils selected from Camphor, turpentine oil, Cedarwood oil and Safrole oil, along with 0.5-2% Wt. of Thymol and 0.25-1% Wt. of preservative/antioxidant.
 
8  Improved anti-dermatophytic preparation and use thereof
SPS Khanuja,
Pushplata Chaturvedi,
AK Singh,
AK Shasany,
VK Agarwal,
VK Gupta,
SC Gupta,
AK Tripathi,
Anirban Pal,
Dharmendra Saikia,
MP Darokar,
KK Agarwal,
RP Bansal
India/234314/20.5.2009
 
The invention provides an improved preparation based on the synergistic action of garlic extract and essential oil of M. spicata var. Ganga or cinnamon oil against dermatophytic fungi. More particularly, invention relates to the synergistic enhancement of activity of a combination by methyl acetate or geraniol. The invention also provides a method of preparation of the synergistic combination and the shelf life observed to be more than one year. The cream based preparation is a potent anti-dermatophytic as described and illustrated by in vitro and in vivo evaluations.
 
9 Composition and process for preparing herbal disinfectants and their use  SPS Khanuja,
MP Darokar,
TRS Kumar,
AK Shasany,
KK Agarwal,
Atique Ahmed,
P Chaturvedi,
VK Gupta,
Alok Krishna,
AK Singh,
JR Bahl,
RP Bansal,
Dinesh Kumar
India/233624/31.3.2009
 
 
The invention relates to development of the disinfectants that are non-toxic, biosafe and in addition give pleasant odour. The disinfectants already available in the market contain harmful chemicals such as formaldehyde, ethane dialdehyde, n-propanol, benzalkonium chloride, and phenol. The present invention relates to disinfectant compositions for cleaning the skin of humans and for cleaning surfaces such as floors. The compositions are homogeneous, clear and also useful as disinfectant. The invention also provides as process for the preparation of the cleaning composition. The compositions are prepared by mixing the components in a particular well-defined order to obtain clear, transparent solutions effective against pathogenic bacteria and fungi.
 
10  A process for the preparation of analgesic & refreshing herbal composition useful as dentifrices  AK Singh,
RL Bindra,
Rashmi Gupta,
YN Shukla,
Sushil Kumar
India/194983/17.3.2006
 
 
Analgesic and refreshing composition has been developed from the extract of betel leaves (Piper betel) and essential oils selected from Lavender, Mentha, Fennel and Ocimum species and their isolates.The composition gives instant relief to toothache and provide freshness to oral cavity. The essential oils used in the composition have antimicrobial activities and can also be developed as herbal mouthwash of plant origin.
 
11 A formulation of herbal biscuits for lactating mothers acting as dietary supplement and the process for preparation thereof
AK Singh,
RL Bindra,
Janardan Singh,
Sushil Kumar
India/230880/28.2.2009
 
 
The said knowledge based composition contains phytomedicinal combination having lactogenic properties, which increase the secretion of mammary glands. The ingredients in the composition provide a source of carbohydrates, proteins, fats and essential nutrients which are important for lactating mothers.
 
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